Digital Record

The weekly newsletter of the Digital Preclinical Society. Application-first coverage of the regulatory shifts, methods, and decisions reshaping preclinical drug development. Free, weekly.

Weekly Issues

FDA

May 14, 2026

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11 min read

THE DIGITAL RECORD

Issue #1 · Thursday, May 14, 2026

Szczepan Baran, +1

Featured

NAMs in 2026: the regulator went AI-first. The data did not.

May 10, 2026

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9 min read

NAMs in 2026: the regulator went AI-first. The data did not.

Stefano Gaburro

Pain Score

May 10, 2026

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7 min read

AI Pain Scores in Drug R&D: Useful, Until You Trust Them

Szczepan Baran

Digital Measures: Why They Count as New Approach Methodologies (NAMs)

Apr 6, 2026

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3 min read

Digital Measures: Why They Count as New Approach Methodologies (NAMs)

Szczepan Baran

Articles

Drug Development

On the same scale: a measurement only travels when it is tied to a shared standard.

Jul 28, 2026

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3 min read

On the same scale: a measurement only travels when it is tied to a shared standard.

Stefano Gaburro

Drug Development

A number you can act on: when a method's stated confidence is worth trusting.

Jul 27, 2026

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3 min read

A number you can act on: when a method's stated confidence is worth trusting.

Szczepan Baran

Read-across, generalized: the transferable evidence pattern hiding in European chemical law.

Jul 21, 2026

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3 min read

Read-across, generalized: the transferable evidence pattern hiding in European chemical law.

Stefano Gaburro

Triage the signal: not every preclinical finding deserves a program decision.

Jul 20, 2026

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3 min read

Triage the signal: not every preclinical finding deserves a program decision.

Szczepan Baran

Weighing, not counting: Europe's weight-of-evidence template for integrating evidence that does not agree.

Jul 19, 2026

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3 min read

Weighing, not counting: Europe's weight-of-evidence template for integrating evidence that does not agree.

Stefano Gaburro

Write it down: the one-page decision-context spec a program should carry like a passport.

Jul 19, 2026

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3 min read

Write it down: the one-page decision-context spec a program should carry like a passport.

Szczepan Baran